Myelin Basic Protein兔單克隆抗體

價(jià)格￥600
規格100ul
貨號HKZ150205
單位支
品牌HaoKebio

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產(chǎn)品參數

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品牌	商品編碼	商品名稱(chēng)	規格	單位	單價(jià)
HaoKebio	HKZ150205	Myelin Basic Protein兔單克隆抗體	100ul	支	600

Myelin?Basic?Protein
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50082?Clone# ?BP6087
Predicted?Molecular Wt:
14~22kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P02686
Background:
Myelin?basic?protein?(MBP)?is the second?most abundant?protein?in central?nervous system?(CNS)?myelin:?it?comprises?30%?of?the total?protein and about?10% of the?dry weight?of?myelin.?It?is?the?only?structural?protein?found?so?far?to?be?essential?for?????formation of CNS?myelin, and?has?been called the?‘executive?molecule?of?myelin’?.
MBP can?interact with a?number of?polyanionic?proteins?including?actin, tubulin,?calmodulin,?and?clathrin,?and?negatively
charged?lipids, and acquires structure on?binding to?them.?It?may?act?as?a?membrane?actin-binding?protein,?which?might?allow?it to?participate?in transmission of extracellular signals to the?cytoskeleton?in?oligodendrocytes?and?tight junctions?in?myelin.
MBP?may?be applicable as a?marker for?oligodendrogliomas.Subcellular?location:
Cytoplasm and?Membrane
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?residues within?aa150-250 of?Myelin?Basic?Protein?was?used?as?an ???immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1. ?Boggs?J?M?.?Cellular?and?Molecular?Life?Sciences?(CMLS),?2006, 63(17):1945-1961.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of
Glioma?labelling?MBP
with?BP6087.?Heat
mediated?antigen
retrieval?was?performed?using Tris/EDTA?buffer????pH?9.0

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