• Melan A兔單克隆抗體

    Melan A兔單克隆抗體

    • 價(jià)格¥1400
    • 規格100ul
    • 貨號HKZ150204
    • 單位
    • 品牌HaoKebio

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    HaoKebioHKZ150204Melan A兔單克隆抗體100ul1400
    Melan-A
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50081?Clone# ?BP6086
    Predicted?Molecular Wt:
    13kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID:??Q16655
    Background:
    Melan-A?is?involved?in?melanosome?biogenesis?by ensuring the stability of GPR143?and?plays?a?vital?role?in?the?expression,????stability, trafficking, and?processing of?melanocyte?protein?PMEL, which?is critical to?the?formation?of?stage?II?melanosomes.
    Melan-A?is specifically expressed?in?malignant?melanoma.
    Melan-A?is one of the?most valuable?melanoma?markers.?Melan-A?is?useful?in confirming?melanocytic?differentiation?of?primary cutaneous tumours, differentiating these from?neurothekeoma and?benign?fibrous?histiocytoma.
    Subcellular?location:
    Cytoplasm
    Recommended?Method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Full?length?protein corresponding to?Human?Melan-A.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage Conditions:
    -25°C?to?-18°C
    Shipment?Instructions:
    Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
    Recommended?Dilution:
    IHC-P:?????1:100-1:200
    Background?References:
    1. ?Hoashi?T., Watabe?H.,?Muller?J.,Vieira?W.D.,?Hearing V.J.J.?Biol. Chem.?280:14006-14016(2005)
    2.?Giordano?F.,?Bonetti?C., Surace?E.M.,?Marigo?V.,?Raposo G.Hum.?Mol. Genet.?18:4530-4545(2009)
    Immunohistochemistry?(Formalin/PFA-fixed?paraffin-?embedded?sections)?analysis of?malignant?melanoma?labelling?Melan-A?with?BP6086.

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