• AEG-1兔多克隆抗體

    AEG-1兔多克隆抗體

    • 價(jià)格￥2800
    • 規格200ul
    • 貨號HK210004L
    • 單位支
    • 品牌HaoKebio

    產(chǎn)品介紹
    產(chǎn)品參數
    資料下載
    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHK210004LAEG-1兔多克隆抗體200ul支2800

    Applications

    Tested Applications:
    IF, IHC, IP, WB,ELISA

    Cited Applications:
    CoIP, IF, IHC, IP, WB
    Species Specificity:
    human, mouse, rat

    Cited Species:
    human, rat

    Positive WB detected in:
    MCF-7 cells, PC-3 cells, A375 cells, HepG2 cells, HeLa cells, RAW 264.7 cells, mouse spleen tissue, DU 145 cells, A549 cells, HL-60 cells

    Positive IP detected in:
    MCF-7 cells

    Positive IHC detected in:
    human breast cancer tissue, mouse brain tissue, human liver cancer tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Positive IF detected in:
    MCF-7 cells

    Recommended dilution:
    WB : 1:500-1:2000
    IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
    IHC : 1:200-1:800
    IF : 1:20-1:200
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information

    Full name:
    metadherin

    Calculated molecular weight:
    582 aa, 64 kDa

    Observed molecular weight:
    65-70 kDa

    Gene symbol
    MTDH

    Synonyms
    3D3, 3D3/LYRIC, AEG 1, AEG1, LYRIC, LYRIC/3D3, metadherin, Metastasis adhesion protein, MTDH, Protein LYRIC
    Background
    MTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22 , the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma , and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH.

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