• AI兔多克隆抗體

    AI兔多克隆抗體

    • 價(jià)格¥1960/¥2800
    • 規格100ul/200ul
    • 貨號HK210005M/HK210005L
    • 單位
    • 品牌HaoKebio

    產(chǎn)品介紹
    產(chǎn)品參數
    資料下載
    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHK210005MAI兔多克隆抗體100ul1960
    HaoKebioHK210005LAI兔多克隆抗體200ul2800

    Applications


    Tested Applications:
    IF, IHC, IP, WB,ELISA

    Cited Applications:
    IF, IHC, WB
    Species Specificity:
    human, mouse, rat

    Cited Species:
    human, mouse, rat, sheep

    Positive WB detected in:
    HeLa cells, Jurkat cells, A549 cells, rat kidney tissue, NIH/3T3 cells

    Positive IP detected in:
    HeLa cells

    Positive IHC detected in:
    human kidney tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Positive IF detected in:
    HepG2 cells

    Recommended dilution:
    WB : 1:1000-1:8000
    IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB
    IHC : 1:100-1:400
    IF : 1:10-1:100
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information

    Full name:
    apoptosis-inducing factor, mitochondrion-associated, 1

    Calculated molecular weight:
    609 aa, 66 kDa

    Observed molecular weight:
    67 kDa, 57 kDa

    Gene symbol
    AIFM1

    Synonyms
    AIF, AIFM1, PDCD8
    Background
    Apoptosis-inducing factor (AIF) is one of the mitochondrial proteins to be released into the cytosol during apoptosis, and it is discovered as the first protein that regulates caspase-independent apoptosis(PMID:20494118). AIF is encoded as a 67 kDa protein that contains a mitochondrial localization signal (MLS) in the N-terminus.It is cleaved from the 62 kDa to the 57 kDa form following ischemic injury and translocated from the mitochondria to the nucleus in a calpain-dependent manner(PMID:19332058).

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