• Calc itonin兔單克隆抗體

    Calc itonin兔單克隆抗體

    • 價(jià)格¥600
    • 規格100ul
    • 貨號HKZ150247
    • 單位
    • 品牌HaoKebio

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    HaoKebioHKZ150247Calc itonin兔單克隆抗體100ul600
    Calcitonin
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50124?Clone# ?BP6128
    Predicted?Molecular Wt:
    15.5kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID: ??P01258
    Background:
    Calcitonin?(CT)?is a?32 amino acid?peptide synthesized?by the?parafollicular?C?cells?of the?thyroid.?It?acts?through?its?receptors
    to?inhibit osteoclast?mediated?bone?resorption, decrease calcium?resorption?by?kidney and?decrease?calcium?absorption?by
    intestines. The action of calcitonin?is therefore to?cause a?reduction?in?serum?calcium,?an?effect?opposite?to?that?of?parathyroid?hormone.
    The antibody?is?useful for the?identification of calcitonin-producing?C?cells and?is?a?useful?aid?for?classification?of?medullary?thyroid carcinoma.
    ?Subcellular?location:
    Cytoplasm
    Recommended?method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide corresponding to?residues?in?Human?Calcitonin was?used as an?immunogen.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage conditions:
    -25°C?to?-18°C
    Storage instructions:
    Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
    Recommended?Dilutions:
    IHC-P:?????1:100-1:200
    Background?References:
    1.?Xing?R??etal.?Int?J?Mol?Med?38:1125-34?(2016).
    2. ?Ramasamy?SK??et?al.?Nat?Commun?7:13601?(2016).
    Immunohistochemistry?(Formalin/PFA-fixed
    paraffin-embedded
    sections)?analysis of
    medullary thyroid
    carcinoma?labelling
    Calcitonin?with?BP6128.??Heat?mediated?antigen???retrieval was?performed?using Tris/EDTA?buffer????pH?9.0.

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