• Nestin兔單克隆抗體

    Nestin兔單克隆抗體

    • 價(jià)格¥2200
    • 規格100ul
    • 貨號HKZ150421
    • 單位
    • 品牌HaoKebio

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    HaoKebioHKZ150421Nestin兔單克隆抗體100ul2200
    Nestin
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50298?Clone# ?BP6275
    Predicted?Molecular Wt:
    177kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID: ??P48681
    Background:
    Nestin?is an?intermediate filament family?member?protein that?is structurally?related to the?neurofilament?proteins.?It?is?highly?expressed?in the developing?brain, where?it?may?help to?regulate cell structure?and?intracellular?processes?required?for?neural??cell division?and?migration.
    Research studies?have shown that expression of?nestin?is?also?found?in?cells?from?various?nervous?system?tumors,?including?gliomas,?neuroblastomas, astrocytomas, and?it?is generally accepted?as?a?marker?for?neural?cancer?stem?cells.
    Nestin expression?is significantly?increased?in?melanoma and correlated?with?more?advanced?stages?of the?disease.
    Subcellular?location:
    Cytoplasm
    Recommended?Method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide. This?information?is?proprietary to?Biolynx.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage Conditions:
    -25°C?to?-18°C
    Shipment?Instructions:
    Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
    Recommended?Dilution:
    IHC-P:?????1:100-1:200
    Background?References:
    1.?Giliarov, A.V.?(2007)?Morfologiia?131, 85-90.
    2.?Gilyarov, A.V.?(2008)?Neurosci?Behav?Physiol?38,?165-9.
    Immunohistochemistry?(Formalin/PFA-fixed?paraffin-embedded?sections)?analysis?of??human?tonsil?labelling?Nestin?with?BP6275.

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