• FIS1兔多克隆抗體

    FIS1兔多克隆抗體

    • 價(jià)格￥1200/￥2800
    • 規格50ul/200ul
    • 貨號HK210146S/HK210146L
    • 單位支
    • 品牌HaoKebio

    產(chǎn)品介紹
    產(chǎn)品參數
    資料下載
    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHK210146SFIS1兔多克隆抗體50ul支1200
    HaoKebioHK210146LFIS1兔多克隆抗體200ul支2800

    Applications

    Tested Applications:
    IF, IHC, IP, WB, ELISA

    Cited Applications:
    CoIP, IF, IHC, IP, WB
    Species Specificity:
    human, mouse, rat, pig

    Cited Species:
    bovine, Chinese hamster ovary (CHO) cell, hamster, human, mouse, pig, rat, squirrel

    Positive WB detected in:
    HeLa cells, SH-SY5Y cells, pig brain tissue, rat brain tissue, mouse heart tissue, rat heart tissue, mouse brain tissue, Jurkat cells, mouse spleen, rat spleen

    Positive IP detected in:
    HeLa cells

    Positive IHC detected in:
    rat brain tissue, human brain tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Positive IF detected in:
    Hepa1-6 cells, HepG2 cells

    Recommended dilution:
    WB : 1:500-1:3000
    IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
    IHC : 1:50-1:500
    IF : 1:50-1:200
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information

    Full name:
    fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)

    Calculated molecular weight:
    17 kDa

    Observed molecular weight:
    17 kDa

    Gene symbol
    FIS1

    Synonyms
    CGI 135, FIS1, FIS1 homolog, hFis1, TPR repeat protein 11, TTC11
    Background
    Fis1 (fission 1) is an integral mitochondrial outer membrane protein that participates in mitochondrial fission by interacting with dynamin-related protein 1 (Drp1). Excessive mitochondrial fission is associated with the pathology of a number of neurodegenerative or neurodevelopmental diseases. Increased expression of Fis1 has been found in Huntington’s disease (HD)-affected brain, Alzheimer’s disease (AD) patients, and autism spectrum disorder. This antibody was raised against the full-length of human Fis1 protein, and recognizes endogenous Fis1 protein in various lysates. (PMID: 21257639, 21459773, 23333625)

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