TPO Mouse Monoclonal Antibody Product Datasheet Catalog# BX50206 Clone# BPM6183 Predicted Molecular Wt: 103kDa Purity: ProA affinity purified IgG Species Cross-reactivity: Human Form: Liquid Applications: IHC-P Swissprot ID: P07202 Background: Thyroid peroxidase (TPO) is a thyroid-specific enzyme involved in thyroid hormone synthesis. TPO can be found in normal thyroid and thyroid carcinoma of papillary and follicular type. Studies indicate that TPO is a useful marker for the differentiation of benign and malignant thyroid neoplasms. Subcellular location: Cytoplasm Recommended method: Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes. Immunogen: Synthetic peptide corresponding to Human TPO protein was used as an immunogen. The exact sequence is proprietary. Storage Buffer: PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. Storage conditions: -25°C to -18°C Storage instructions: Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles. Recommended Dilutions: IHC-P: 1:100-1:200 Background References: 1. Savin S, et al. Hum Pathol. 2008; 39:1656-63. 2. Yousaf U, et al. Clin Endocrinol (Oxf). 2005; 68:996- 1001. Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of thyroid gland labelling TPO with BPM6183. Heat mediated antigen retrieval was performed using Tris/EDTA buffer pH 9.0
杭州浩克生物
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