• CD3兔單克隆抗體

    CD3兔單克隆抗體

    • 價(jià)格¥600
    • 規格100ul
    • 貨號HKZ150157
    • 單位
    • 品牌HaoKebio

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    HaoKebioHKZ150157CD3兔單克隆抗體100ul600
    CD3
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    ?
    Catalog# BX50034?Clone# ?BP6039
    ?
    Predicted?Molecular Wt:
    23kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID: ??P07766
    Background:
    Cluster?of?differentiation?3?(CD3)?is?a?multimeric
    protein complex,?known?historically as the T3 complex,?and?is composed of four distinct?polypeptide?chains;
    epsilon?(ε), gamma?(γ), delta?(δ) and?zeta?(ζ),?that
    assemble?and?function?as?three?pairs?of?dimers?(εγ,?εδ,??ζζ). The?CD3 complex?serves?as?a?T?cell?co-receptor?that associates?noncovalently with the T cell?receptor?(TCR).
    ?
    CD3 antigen appearance at?all?stagesofT?cell
    development, and?makes?it anideal T cell?marker?for?both the detection of?normal T?cells?and?T?cell
    neoplasms?(lymphomas and?leukemias).
    Subcellular?location:
    Membrane
    Recommended?method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide corresponding to CD3E?residues
    within?aa100-200 of?CD3E?was?used?as?an?immunogen.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage conditions:
    -25°C?to?-18°C
    Storage instructions:
    Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
    Recommended?Dilutions:
    IHC-P:?????1:100-1:200
    Background?References:
    1.?Smith-Garvin?JE, et.al, Annu?Rev?Immunol.?2009;27:591-619.
    2.?SalvadoriS, et.al, J?Immunol.?1994?Dec?1;153(11):5176-?82.
    Immunohistochemistry?(Formalin/PFA-fixed
    paraffin-embedded
    sections analysis?of tonsil?tissue?labelling?CD3 with??BP6039.?Heat?mediated ???antigen?retrieval was
    performed?using
    Tris/EDTA?buffer?pH?9.0

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