• ARL13B兔多克隆抗體

    ARL13B兔多克隆抗體

    • 價(jià)格¥2800
    • 規格200ul
    • 貨號HK210015L
    • 單位
    • 品牌HaoKebio

    產(chǎn)品介紹
    產(chǎn)品參數
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    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHK210015LARL13B兔多克隆抗體200ul2800

    Applications


    Tested Applications:
    IF, IHC, IP, WB,ELISA

    Cited Applications:
    IF, IHC, IP, WB
    Species Specificity:
    human, mouse, rat, Canine

    Cited Species:
    canine, chicken, human, mouse, pig, rat, sheep, Xenopus, zebrafish

    Positive WB detected in:
    mouse liver tissue, NIH/3T3 cells, L02 cells, mouse kidney tissue, rat liver tissue, mouse brain tissue

    Positive IP detected in:
    L02 cells

    Positive IHC detected in:
    mouse brain tissue, human testis tissue, human liver tissue, human kidney tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Positive IF detected in:
    MDCK cells, hTERT-RPE1, mouse embryonic fibroblasts, NIH3T3 cells

    Recommended dilution:
    WB : 1:500-1:2000
    IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
    IHC : 1:50-1:500
    IF : 1:50-1:500
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information

    Full name:
    ADP-ribosylation factor-like 13B

    Calculated molecular weight:
    48 kDa

    Observed molecular weight:
    40-48 kDa, 66 kDa

    Gene symbol
    ARL13B

    Synonyms
    ARL13B, ARL2 like protein 1, ARL2L1, JBTS8
    Background
    ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870).This antibody detects two speci?c bands at 60 kDa and 48 kDa. Arl13b is predicted to be a 48 kDa protein, and the 60 kDa band is likely to represent a modified form of Arl13b. ARL13B can be used to mark the cilia (PMID:22072986).

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