• BIP兔多克隆抗體

    BIP兔多克隆抗體

    • 價(jià)格¥1200¥2800
    • 規格50ul/200ul
    • 貨號HK210047S/HK210047L
    • 單位
    • 品牌HaoKebio

    產(chǎn)品介紹
    產(chǎn)品參數
    資料下載
    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHK210047SBIP兔多克隆抗體50ul1200
    HaoKebioHK210047LBIP兔多克隆抗體200ul2800


    Applications


    Tested Applications:
    FC, IF, IHC, IP, WB,ELISA

    Cited Applications:
    CoIP, IF, IHC, IP, WB

    Species Specificity:
    human, mouse, rat

    Cited Species:
    bovine, carp, chicken, deer, fish, Hamster, human, mouse, pig, rat

    Positive WB detected in:
    HEK-293 cells

    Positive IP detected in:
    MCF-7 cells

    Positive IHC detected in:
    mouse kidney tissue, human breast cancer tissue, human pancreas cancer tissue, mouse heart tissue, rat brain tissue, human colon cancer tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Positive IF detected in:
    HepG2 cells

    Positive FC detected in:
    HeLa cells

    Recommended dilution:
    WB : 1:1000-1:6000
    IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
    IHC : 1:50-1:500
    IF : 1:50-1:500
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information

    Full name:
    heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)

    Calculated molecular weight:
    78 kDa

    Observed molecular weight:
    70-78 kDa

    Gene symbol
    HSPA5

    Synonyms
    BIP, GRP 78, GRP78, HSP A5, HSPA5, MIF2
    Background
    GRP78 (HSPA5), also referred to as ‘immunoglobulin heavy chain-binding protein’ (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).It is a constitutively expressed resident protein of the ER in all eukaryotic cells. Recently it has been reported that GRP78 is associated with apoptosis or inhibition of cancer cell growth. 11587-1-AP antibody recognizes one or two bands with MW 70-78 kDa for the signal peptide of GRP78 protein can be finally cleaved.

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