• CK5&6兔單克隆抗體

    CK5&6兔單克隆抗體

    • 價(jià)格￥600
    • 規格100ul
    • 貨號HKZ150398
    • 單位支
    • 品牌HaoKebio

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    HaoKebioHKZ150398CK5&6兔單克隆抗體100ul支600
    CK5&6
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50275?Clone# ?BP6252
    Predicted?Molecular Wt:
    62/60kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID: ??P13647/P02538/P04259/P48668
    Background:
    Cytokeratin?5?is a?basic?protein that?is closely?related to cytokeratin?6. They?share?similar?tissue?distribution?and?are?found?in???various?proportions?in?many?non-keratinizing stratified squamous epithelia eg. tongue?mucosa,?as?well?as?in?basal?epithelia?of?trachea,?basal cells of epidermis,?hair follicles, sebaceous?and?sweat?glands?of?skin,?luminal?cells?of the?mammary?gland,?basal?cells of?prostate,?urothelium, vagina and endocervical?mucosa.
    Cytokeratins 5 and?6 are also?expressed?in?basal?cell?epitheliomas,?squamous?cell?carcinomas?of?skin, tongue,?epiglottis?and?of?the?rectal-anal?region.?Point?mutations?in?the?cytokeratin?5 gene?at?locus?12q11-q13?can?cause?various?types?of?epidermolysis bullosa simplex.
    Subcellular?location:
    Cytoplasmic
    Recommended?Method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide. This?information?is?proprietary to?Biolynx.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage Conditions:
    -25°C?to?-18°C
    Shipment?Instructions:
    Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.
    Recommended?Dilution:
    IHC-P:?????1:100-1:200
    Background?References:
    1. ?Mukhopadhyay?S., et.al. ?Am?J?Surg?Pathol.?2011 Jan;?35(1):15-25.
    2. ??KargiA, Gurel?D., et.al. Appl?Immunohistochem?Mol Morphol.?2007?Dec;?15(4):415-20.
    Immunohistochemistry?(Formalin/PFA-fixed?paraffin-????embedded?sections)?analysis of ?human cervical?cancer?labelling?CK5&6 with?BP6252

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