• TRPS1兔單克隆抗體

    TRPS1兔單克隆抗體

    • 價(jià)格¥1800
    • 規格100ul
    • 貨號HKZ150377
    • 單位
    • 品牌HaoKebio

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    HaoKebioHKZ150377TRPS1兔單克隆抗體100ul1800
    TRPS1
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50254?Clone# ?BP6231
    Predicted?Molecular Wt:
    141kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID:??Q9UHF7
    Background:
    TRPS1?is a transcription factor that was?initially discovered?as?being?mutated?in Tricho-rhino-phalangeal?syndrome,?a
    craniofacial and skeletal?malformation syndrome. TRPS1?recognizes GATA?sequences?and?represses the?activation?potential?of?other GATA factors.?In addition, TRPS1?binds to the?NuRD?complex via?CHD4?and?can?repress?other?key transcription?factors
    such asp63 and?estrogen?receptor.
    TRPS1?is?highly expressed?in?breast cancer, cervix, esophageal?epithelium.
    TRPS1?is?used as a sensitive and?specific?marker?of?breast?cancer?in?pathological?diagnosis.
    Subcellular?location:
    Nucleus
    Recommended?Method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Recombinant?protein fragment of TRPS1 was?used as?an?immunogen.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage Conditions:
    -25°C?to?-18°C
    Shipment?Instructions:
    Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?-18?°C. Avoid?freeze?/ thaw?cycles.
    Recommended?Dilution:
    IHC-P:?????1:100-1:200
    Background?References:
    1.?Serandour, A.A. et?al.?(2018) Oncogene?37,?5281-91.
    2.?Wang, Y. et?al.?(2018)?Oncogenesis?7,?96.
    Immunohistochemistry?(Formalin/PFA-fixed?paraffin-????embedded?sections)?analysis of?breast cancer?labelling?TRPS1 with?BP6231.

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