• O lig2兔單克隆抗體

    O lig2兔單克隆抗體

    • 價(jià)格¥600
    • 規格100ul
    • 貨號HKZ150312
    • 單位
    • 品牌HaoKebio

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    HaoKebioHKZ150312O lig2兔單克隆抗體100ul600
    Olig2
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50189?Clone# ?BP6167
    Predicted?Molecular Wt:
    32kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID:??Q13516
    Background:
    Olig2, a?basic?helix–loop–helix transcription factor,?is?involved?in oligodendroglial specification.?Olig2?expression?has?been
    reported?in?most glial tumors, such asoligodendrogliomas and?astrocytomas. Although?more?than?half?of?glioblastomas?are
    positive for?Olig2, expression?is very weak?in terms of?both?percentage?of?labeled?cells?and?intensity.?No?Olig2?expression?has????been found?in the?non-glial tumors?including?neuroepithelial tumors, ependymomas, subependymomas,?medulloblastomas,?????and?nonneuroepithelial tumors, such as CNS?lymphomas,?meningiomas, schwannomas,?atypical teratoid/rhabdoid?tumor,?and?haemangioblastomas. Compared to the strong staining seen?in?glioma?samples,?a?weak?expression?is?observed?in?non-tumoral??brain tissue.
    Subcellular?location:
    Nucleus
    Recommended?method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide corresponding to?residues?in?Human?Olig2 was?used as?an?immunogen.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage conditions:
    -25°C?to?-18°C
    Storage instructions:
    Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
    Recommended?Dilutions:
    IHC-P:?????1:100-1:200
    Background?References:
    1.?Shou?JW??etal.?Front?Cell?Neurosci?13:395?(2019).
    2.?Cho?KHT??etal. Sci?Rep?10:6904?(2020).
    Immunohistochemistry?(Formalin/PFA-fixed
    paraffin-embedded
    sections)?analysis
    of??human?brain tissue?labelling Olig2?with
    BP6167.?Heat?mediated antigen?retrieval was
    performed?using
    Tris/EDTA?buffer?pH?9.0

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