• AR-V7兔單克隆抗體

    AR-V7兔單克隆抗體

    • 價(jià)格￥1000
    • 規格100ul
    • 貨號HKZ150297
    • 單位支
    • 品牌HaoKebio

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    HaoKebioHKZ150297AR-V7兔單克隆抗體100ul支1000
    AR?V7
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50174?Clone# ?BP6152
    Predicted?Molecular Wt:
    80kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID:??C0JKD3
    Background:
    AR V7?belongs to the?nuclear?hormone?receptor family.?It Contains?nuclear?receptor?DNA-binding domain.?Steroid?hormone
    receptors are?ligand-activated transcription factors that?regulate eukaryotic gene?expression?and?affect?cellular?proliferation????and differentiation?in target tissues. Transcription factor activity?is?modulated?by?bound?coactivator?and?corepressor?proteins.?This?target?is?a?splice?variant?of?Androgen?receptor?(UniProt?P10275)?lacking?the?C-terminal?androgen?binding?site.
    Subcellular?location:
    Nucleus
    Recommended?method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide?(the amino acid sequence?is
    considered to?be commercially sensitive) within?Human?Androgen?Receptor(AR-V7 specific) aa?600 to?the?C-
    terminus.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage conditions:
    -25°C?to?-18°C
    Storage instructions:
    Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
    Recommended?Dilutions:
    IHC-P:?????1:100-1:200
    Background?References:
    1.?Chen?W??etal. J?Cell?Biochem?120:14055-14064?(2019).
    2.??Honda?M??etal.?Prostate?79:1043-1052?(2019).
    Immunohistochemistry?(Formalin/PFA-fixed
    paraffin-embedded sections)?analysis of?prostate
    adenocarcinoma tissue
    labelling AR V7??with
    BP6152.?Heat?mediated
    antigen?retrieval?was
    performed?using Tris/EDTA?buffer?pH?9.0

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