• Cytokeratin 5&6兔單克隆抗體Cocktail

    Cytokeratin 5&6兔單克隆抗體Cocktail

    • 價(jià)格￥600
    • 規格100ul
    • 貨號HKZ150267
    • 單位支
    • 品牌HaoKebio

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    HaoKebioHKZ150267Cytokeratin 5&6兔單克隆抗體Cocktail100ul支600
    Cytokeratin?5&6
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50144 Clone#??BP6021&BP6065
    Predicted?Molecular Wt:
    62/60kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID: ??P13647/P48668
    Background:
    Cytokeratin?5?is a?basic?protein that?is closely?related to cytokeratin?6. They?share?similar?tissue?distribution?and?are?found?in??various?proportions?in?many?non-keratinizing stratified squamous epithelia?(e.g. tongue?mucosa), as?well?as?in?basal?epithelia?of trachea,?basal cells of epidermis,?hair follicles, sebaceous?and?sweat?glands?of?skin,?luminal?cells?of the?mammary?gland,
    basal cells of?prostate,?urothelium, vagina and?endocervical?mucosa.?Cytokeratins 5?and?6?are?also?expressed?in?basal?cell?epitheliomas, squamous cell carcinomas of skin,?tongue,?epiglottis?and?of the?rectal-anal?region.
    Cytokeratin?5&6?is a?useful aid for classification?of epithelioid?mesotheliomas.
    Subcellular?location:
    Cytoplasm
    Recommended?method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide?according?to?the?aa490-590?(C-
    terminal) of ?cytokeratin 5 was?used?as?an?immunogen.?Synthetic?peptide corresponding to?Cytokeratin 6
    residues?within?aa464-564 of??Cytokeratin?6?was?used as an?immunogen.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage conditions:
    -25°C?to?-18°C
    Storage instructions:
    Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
    Recommended?Dilutions:
    IHC-P:?????1:50-1:100
    Background?References:
    1. ?R?Mollet?al.?Histochem?Cell?Biol?(2008)?129:705–733.
    2. ?R?Mollet?al.?Cell, Vol.?31,?1?l-24,?November?1982.Immunohistochemistry?(Formalin/PFA-fixed
    paraffin-embedded
    sections)?analysis of
    cervix tissue?labelling
    Cytokeratin?5&6?with
    BP6021&BP6065.?Heat mediated?antigen
    retrieval?was?performed?using Tris/EDTA?buffer ph.90

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