• PAX-5兔單克隆抗體

    PAX-5兔單克隆抗體

    • 價(jià)格￥1000
    • 規格100ul
    • 貨號HKZ150259
    • 單位支
    • 品牌HaoKebio

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    HaoKebioHKZ150259PAX-5兔單克隆抗體100ul支1000
    PAX-5
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50136?Clone# ?BP6140
    Predicted?Molecular Wt:
    42kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID:??Q02548
    Background:
    Pax genes area family of developmental?control genes?that?encode?nuclear?transcription?factors?and?have?been?implicated?in?the control of?mammalian?development.
    PAX-5?is a?marker for?B-cells,?including?B-lymphoblastic?neoplasms and?maturation stage.?It?is found?in?most?cases?of?mature???and?precursor?B-cell?non-Hodgkin?lymphomas/leukemias.?In approximately 97% of cases?of classic?Hodgkin?lymphoma,?Reed-?Sternberg cells express?PAX-5.
    The antibody?is a?useful tool for the?identification of?pro,?pre,?and?mature?B?cells?and?for?classification?of?lymphomas?and?subclassification of classic?Hodgkin’s?lymphoma and anaplastic?large?cell?lymphoma?of the T?and?null-cell?type.
    Subcellular?location:
    Nucleus
    Recommended?method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide corresponding to?residues within
    aa300 to?aa400 of?PAX-5 was?used?as?an?immunogen.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage conditions:
    -25°C?to?-18°C
    Storage instructions:
    Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
    Recommended?Dilutions:
    IHC-P:?????1:100-1:200
    Background?References:
    1.?Abdelrasoul?H??etal. Sci?Rep?8:1327?(2018).
    2. ?Hijano?DR??etal. Sci?Rep?8:11034?(2018)
    Immunohistochemistry
    (Formalin/PFA-fixed
    paraffin-embedded
    sections)?analysis of tonsil?labelling?PAX-5?with
    BP6140.?Heat?mediated antigen?retrieval?was
    performed?using
    Tris/EDTA?buffer?pH?9.0.

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