• CD38兔單克隆抗體

    CD38兔單克隆抗體

    • 價(jià)格¥600
    • 規格100ul
    • 貨號HKZ150200
    • 單位
    • 品牌HaoKebio

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    HaoKebioHKZ150200CD38兔單克隆抗體100ul600
    CD38
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50077?Clone# ?BP6082
    Predicted?Molecular Wt:
    34kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID: ??P28907
    Background:
    CD38, also?known as ADP-ribosyl cyclase, synthesizes the?second?messagers?cyclic?ADP-ribose?and?nicotinate-adenine
    dinucleotide?phosphate, the former a second?messenger for glucose-induced?insulin?secretion.?CD38?also?has?cADPr?hydrolase?activity.?It?is found on?immature cells of the?B?and T?cell?lineages?but?not?on?most?mature?resting?peripheral?lymphocytes.?It?is
    also?present on thymocytes,?pre-B cells, germinal center?B?cells,?mitogen-activated?T?cells,?Ig-secreting?plasma?cells,?monocytes,?NK cells, erythroid and?myeloid?progenitors?in the?bone?marrow?and?brain?cells.
    CD38?isuesd to?identify?plasma cells and?plasmablastic differentiation, and?evaluate?the?prognosis?for?B-cell?chronic?lymphocytic?leukemia?(CLL)?patients.
    Subcellular?location:
    Membrane
    Recommended?method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide corresponding to?residues within?aa200-300 of?CD38 was?used?as?an?immunogen.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage conditions:
    -25°C?to?-18°C
    Storage instructions:
    Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
    Recommended?Dilutions:
    IHC-P:?????1:100-1:200
    Background?References:
    1.?Chini?CC??et?al.?Clin?Cancer?Res?20:120-30?(2014).
    2.??Kobayashi?M??etal. World?J?Gastroenterol?20:3597-608?(2014).
    Immunohistochemistry?(Formalin/PFA-fixed
    paraffin-embedded
    sections)?analysis of
    tonsil?labelling?CD38 with BP6082.?Heat?mediated ???antigen?retrieval?was
    performed?using
    Tris/EDTA?buffer?pH?9.0.

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