• CD1a兔單克隆抗體

    CD1a兔單克隆抗體

    • 價(jià)格￥1000
    • 規格100ul
    • 貨號HKZ150173
    • 單位支
    • 品牌HaoKebio

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    HaoKebioHKZ150173CD1a兔單克隆抗體100ul支1000
    CD1a
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50050?Clone# ?BP6055
    Predicted?Molecular Wt:
    37kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID: ??P06126
    Background:
    CD1a?is?a?member?of?the?family?group?1 CD1?proteins?(CD1a,?CD1b,?and?CD1c),?which?share?the?capacity?to?present?microbial lipid antigens to?T?cells.
    CD1a?is expressed?predominantly on?Langerhans cells?(LCs),?it can?be?expressed?by T-cells?under?certain?conditions.?Immature
    thymocytes express CD1a, as do?some T-cells?involved?in?neoplastic?conditions?such?as?pre-lymphoblastic?lymphomas/leukemias and follicular dendritic cell?sarcoma.
    CD1a expression?on?pathogenic?Langerhans cells?(LCs)?in?LCH?is?regarded as a?hallmark?of this?disease?and?may?as?a?potential?target for future therapeutic strategies against?inflammatory skin?diseases.
    Subcellular?location:
    Membrane
    Recommended?method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide corresponding to CD1a?residues?????within?aa1-100 of?CD1a?was?used?as?an?immunogen.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage conditions:
    -25°C?to?-18°C
    Storage instructions:
    Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
    Recommended?Dilutions:
    IHC-P:?????1:100-1:200
    Background?References:
    1. ?Hunger?RE, et.al, J?Clin?Invest.?2004?Mar;113(5):701-8.
    2.?Ji?Hyung?Kim, et.al,?Nature?Immunology?17
    (10) ,?pp.?1159-1166.
    Immunohistochemistry?(Formalin/PFA-fixed
    paraffin-embedded
    sections analysis?of
    esophagus tissue
    labelling CD1a?with
    BP6055.?Heat?mediated antigen?retrieval?was
    performed?using
    Tris/EDTA?buffer?pH?9.0

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