• CD23兔單克隆抗體

    CD23兔單克隆抗體

    • 價(jià)格￥600
    • 規格100ul
    • 貨號HKZ150167
    • 單位支
    • 品牌HaoKebio

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    HaoKebioHKZ150167CD23兔單克隆抗體100ul支600
    CD23
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50044?Clone# ?BP6049
    Predicted?Molecular Wt:
    36kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID: ??P06734
    Background:
    CD23 antigen?is a transmembrane glycoprotein?by various?hematopoietic cell?types?and?functions?as?a?low-affinity?receptor?for?IgE. CD23?is?involved?in?regulating?IgE?production and?has other?potential?biologic functions,?including?promoting the?survival????of germinal center?B?lymphocytes.
    CD23?is found?in some?mature?B-cell?lymphomas and?in?Reed-Sternberg cells?in?Hodgkin?disease.?Follicular?dendritic cells?and??some activated?B-cells within germinal centers express?CD23?in?high?density?and?mantle?zone?B-cells?are?stained?weakly. The???majority of chronic?lymphocytic?leukemias/small?lymphocytic?lymphomas are CD23?positive, whereas?mantle?cell?lymphomas?are generally?negative.
    CD23?has?been shown to?be?useful for the differentiation of?small?lymphocytic?lymphomas?and?mantle?cell?lymphoma.
    Subcellular?location:
    Membrane
    Recommended?method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide corresponding to CD23?residues
    within?aa221-321 of?CD23 was?used?as?an?immunogen.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage conditions:
    -25°C?to?-18°C
    Storage instructions:
    Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
    Recommended?Dilutions:
    IHC-P:?????1:100-1:200
    Background?References:
    1.?Olteanu?H, et?al. Am?J?Clin?Pathol.?2011 Jan;135(1):46-?53.
    2. ?Kumar?S, et?al.?Mod?Pathol.?1996?Sep;9(9):925-9.
    Immunohistochemistry?(Formalin/PFA-fixed
    paraffin-embedded
    sections analysis?of
    tonsil tissue?labelling
    CD23 with?BP6049.?Heat mediated?antigen
    retrieval?was?performed?using Tris/EDTA?buffer????pH?9.0

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