• Caspase 8兔多克隆抗體

    Caspase 8兔多克隆抗體

    • 價(jià)格￥2800
    • 規格200ul
    • 貨號HK210070L
    • 單位支
    • 品牌HaoKebio

    產(chǎn)品介紹
    產(chǎn)品參數
    資料下載
    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHK210070LCaspase 8兔多克隆抗體200ul支2800


    Applications

    Tested Applications:
    IF, IHC, IP, WB, ELISA

    Cited Applications:
    ELISA, IF, IHC, IP, RIP, WB

    Species Specificity:
    human, mouse

    Cited Species:
    chicken, human, mouse, rabbit, rat

    Positive WB detected in:
    Staurosporine treated Jurkat cells, RAW264.7, HeLa cells, Raji cells, Jurkat cells, UV treated Hela, Sp2/0 cells

    Positive IP detected in:
    HeLa cells, Jurkat cells

    Positive IHC detected in:
    human lymphoma tissue, human colon tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Positive IF detected in:
    HepG2 cells

    Recommended dilution:
    WB : 1:500-1:1000
    IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
    IHC : 1:50-1:500
    IF : 1:10-1:100
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information

    Immunogen:
    Caspase 8/p43/p18 fusion protein Ag4214

    Full name:
    caspase 8, apoptosis-related cysteine peptidase

    Calculated molecular weight:
    538 aa, 62 kDa

    Observed molecular weight:
    53-57 kDa, 32-45 kDa

    Gene symbol
    CASP8

    Synonyms
    Apoptotic protease Mch 5, Casp 8, CASP8, Caspase 8, Caspase 8/p18, Caspase 8/p43/p18, caspase8, FADD like ICE, FLICE, ICE like apoptotic protease 5, MCH5
    Background
    CASP8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. CASP8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816 ). It may control diabetic embryopathy-associated apoptosis via regulation of the Bid-stimulated mitochondrion/caspase-9 pathway (PMID:19194987). CASP8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibody can recognize the pro- and cleaved-caspase 8.

    暫無(wú)

    說(shuō)明文檔下載

    上一篇: 下一篇:

    推薦

    您好！請登錄

    點(diǎn)擊取消回復
      展開(kāi)更多
      點(diǎn)擊展開(kāi)我們的聯(lián)系方式
      丝袜美腿精品国产一区|吉泽明歩一区二区三区中文字幕|超碰97人人模人人爽人人|久久中文字幕永久第一页