PAX-2兔單克隆抗體

價(jià)格￥1000
規格100ul
貨號HKZ150162
單位支
品牌HaoKebio

產(chǎn)品介紹

產(chǎn)品參數

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品牌	商品編碼	商品名稱(chēng)	規格	單位	單價(jià)
HaoKebio	HKZ150162	PAX-2兔單克隆抗體	100ul	支	1000

PAX-2
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
?
Catalog# ?BX50039?Clone# ?BP6044
?
Predicted?Molecular Wt:
45kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID:??Q02962
Background:
PAX-2?is a?member of the?PAX family of transcription factors?that,?together?with?PAX-8,?is?involved?in?the?regulation?of the?organogenesis of the?kidney and the?Müllerian system.
Among the?non-neoplastic tissue,?PAX-2 was expressed?in glomerular?parietal epithelial?cells,?renal?collecting?duct?cells,
atrophic?renal tubular?cells, epithelial cells of?ovarian?surface,?fallopian?tube,?endocervix,?endometrium.?Among?the?primary?neoplasms,?PAX-2 was?mainly?noted?in?renal cell carcinoma, carcinomas?of?Müllerian?origin,?nephrogenic?adenomas.
Recent?investigations?have?indicated that?PAX-2 could serve as a?useful?immunohistochemical?marker?that?can?assist?in?the?diagnosis of epithelial tumors of the?kidney, as well?as?some?gynecologic?(Müllerian)?neoplasms.
Subcellular?location:
Nucleus
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?PAX-2?residues
within?aa300-400 of?PAX-2 was?used?as?an?immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Zhai QJ, et.al,Appl?Immunohistochem?Mol?Morphol.
2010 Jul;18(4):323-32.
2.?Ordó?ez?NG, et.al, Adv?Anat?Pathol.?2012?Nov;19(6):401-9.
Immunohistochemistry?(Formalin/PFA-fixed
paraffin-embedded
sections analysis?of
kidney tissue?labelling?PAX-2 with?BP6044.
Heat?mediated?antigen???retrieval?was?performed?using Tris/EDTA?buffer????pH?9.0

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