COX-2兔單克隆抗體

品牌	商品編碼	商品名稱(chēng)	規格	單位	單價(jià)
HaoKebio	HKI0591B	COX-2兔單克隆抗體	1ml	支	5512.5

Applications

Tested Applications:

IF, IHC, WB, ELISA

---

Cited Applications:

IF, IHC, WB

---

Species Specificity:

human, mouse

---

Cited Species:

human, mouse, rat

---

Positive WB detected in:

A549 cells, mouse lung tissue

---

Positive IHC detected in:

human lung tissue, human spleen tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

---

Positive IF detected in:

mouse lung tissue

---

Recommended dilution:

WB : 1:500-1:1000

IHC : 1:100-1:400

IF : 1:50-1:500

Product Information

---

Source:

Rabbit

---

Purification method:

Antigen affinity purification

---

Isotype:

IgG

---

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Immunogen Information

---

Full name:

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

---

Calculated molecular weight:

604 aa, 68 kDa

---

Observed molecular weight:

69 kDa

---

Gene symbol

PTGS2

---

Synonyms

COX 2, COX2, COX2/ Cyclooxygenase 2, COX2/ Cyclooxygenase 2/ PTGS2, Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2

Background

COX2 (Prostaglandin G/H synthase 2, PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72-74 kDa and the aglycosylated is 66 kDa(PMID:19656660 ). It also expresses a band of 39 kDa after unspecific cleavage(PMID:17509125 ). The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains(PMID:14724276 ).