• ATG13兔多克隆抗體

    ATG13兔多克隆抗體

    • 價(jià)格¥1200
    • 規格50ul
    • 貨號HK210021S
    • 單位
    • 品牌HaoKebio

    產(chǎn)品介紹
    產(chǎn)品參數
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    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHK210021SATG13兔多克隆抗體50ul1200

    Applications


    Tested Applications:
    IF, IHC, IP, WB,ELISA
    Cited Applications:
    WB

    Species Specificity:
    human, mouse, rat

    Cited Species:
    human, mouse, rat

    Positive WB detected in:
    SH-SY5Y cells, mouse thymus tissue, human brain tissue, mouse cerebellum tissue, mouse testis tissue, BGC-823 cells

    Positive IP detected in:
    SH-SY5Y cells

    Positive IHC detected in:
    mouse heart tissue, mouse brain tissue, human brain tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Positive IF detected in:
    SH-SY5Y cells

    Recommended dilution:
    WB : 1:500-1:1000
    IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
    IHC : 1:50-1:500
    IF : 1:50-1:500
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information
    Full name:
    KIAA0652

    Calculated molecular weight:
    57 kDa

    Observed molecular weight:
    57-63 kDa
    Gene symbol
    KIAA0652

    Synonyms
    ATG13, Autophagy related protein 13, KIAA0652
    Background
    ATG13 is one component protein of the ULK1 complex which is required for autophagosome formation and mitophagy. ATG13 has two nutrient regulatory phosphorylation sites and the phosphorylation status of ATG13 affect regulation of autophagy by modulating enzyme activity and cellular localization of ULK1. Besides, it has been reported the nonautophagic function of ATG13 on cardiac development for ATG13-deficient embryos show myocardial growth defects.(PMID:27387056, 26801615, 26644405)

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