• GRP94兔多克隆抗體

    GRP94兔多克隆抗體

    • 價(jià)格￥1200
    • 規格50ul
    • 貨號HK210168S
    • 單位支
    • 品牌HaoKebio

    產(chǎn)品介紹
    產(chǎn)品參數
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    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHK210168SGRP94兔多克隆抗體50ul支1200

    Applications

    Tested Applications:
    FC, IF, IHC, IP, WB,ELISA

    Cited Applications:
    WB
    Species Specificity:
    human, mouse, rat

    Cited Species:
    human, pig, rat

    Positive WB detected in:
    HEK-293 cells, A549 cells, MCF-7 cells, K-562 cells, NIH/3T3 cells

    Positive IP detected in:
    MCF-7 cells

    Positive IHC detected in:
    human breast cancer tissue, human lung cancer tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Positive IF detected in:
    MCF-7 cells, HEK-293 cells

    Positive FC detected in:
    MCF-7 cells

    Recommended dilution:
    WB : 1:500-1:2000
    IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
    IHC : 1:20-1:200
    IF : 1:20-1:200
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information

    Full name:
    heat shock protein 90kDa beta (Grp94), member 1

    Calculated molecular weight:
    96 kDa

    Observed molecular weight:
    94 kDa

    Gene symbol
    HSP90B1

    Synonyms
    ECGP, Endoplasmin, GP96, gp96 homolog, GRP 94, GRP94, HSP90B1, TRA1, Tumor rejection antigen 1
    Background
    HSP90 proteins are highly conserved molecular chaperones, which normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 (GP96 or GRP94) is an endoplasmic reticulum paralogue of the cytosolic HSP90. As a major ER chaperone to mediate the UPR and a master chaperone for Toll-like receptors (TLRs), HSP90b1 chaperones peptides to MHC class I molecules of dendritic cells and other antigen-presenting cells, as well as facilitating the assembly of immunoglobulin. The protein is also involved in many other bio-processes. This antibody was generated against the N-terminal region of full-length HSP90b1.

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