• HSP70兔多克隆抗體

    HSP70兔多克隆抗體

    • 價(jià)格￥2800
    • 規格200ul
    • 貨號HK210178L
    • 單位支
    • 品牌HaoKebio

    產(chǎn)品介紹
    產(chǎn)品參數
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    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHK210178LHSP70兔多克隆抗體200ul支2800

    Applications

    Tested Applications:
    FC, IF, IHC, IP, WB, ELISA

    Cited Applications:
    CoIP, IF, IHC, IP, WB

    Species Specificity:
    human, mouse, rat

    Cited Species:
    bovine, C. elegans, human, mouse, oyster, pig, rat

    Positive WB detected in:
    A431 cells, mouse uterus tissue, mouse kidney tissue, rat brain tissue, A549 cells, HeLa cells, Jurkat cells, mouse brain

    Positive IP detected in:
    mouse brain tissue

    Positive IHC detected in:
    human breast cancer tissue, human liver cancer tissue, mouse skin tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Positive IF detected in:
    HeLa cells, HepG2 cells

    Positive FC detected in:
    HepG2 cells, HeLa cells, A549 cells

    Recommended dilution:
    WB : 1:5000-1:50000
    IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
    IHC : 1:50-1:500
    IF : 1:50-1:500
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information

    Full name:
    heat shock 70kDa protein 1A

    Calculated molecular weight:
    70 kDa

    Observed molecular weight:
    66-70 kDa

    Gene symbol
    HSPA1A

    Synonyms
    Heat shock 70 kDa protein 1/2, heat shock 70kDa protein 1A, HSP70, HSP70 1, HSP70 1/HSP70 2, HSP70 1A, HSP70.1/HSP70.2, HSP70I, HSP72, HSPA1, HSPA1A, HSPA1B
    Background
    HSPA1A , collectively known as HSP70 (also referred to HSP72), is a stress-inducible member of heat-shock protein 70 (HSP70) proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. Encoded by two closely linked, intronless and stress-inducible genes, HSPA1A and HSPA1B differ by only two amino acids and are believed to be fully interchangeable proteins. HSPA1A is a cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Generally, HSPA1A is thought to be expressed in unstressed normal cells at low or undetectable levels. Expression of HSPA1A protein can be highly activated by various stressful stimuli. Significant up-regulation of HSPA1A has been found in various tumors. Recently it has been reported that HSPA1A can be constitutively expressed in selected cell types. HSP70 is a useful marker for exosome. This antibody well recognized the endogenous HSP70 protein in multiple cell lines. (21373891)

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