• Clusterin兔單克隆抗體

    Clusterin兔單克隆抗體

    • 價(jià)格￥1400
    • 規格100ul
    • 貨號HKZ150414
    • 單位支
    • 品牌HaoKebio

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    HaoKebioHKZ150414Clusterin兔單克隆抗體100ul支1400
    Clusterin
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50291?Clone# ?BP6268
    Predicted?Molecular Wt:
    52kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID: ??P10909
    Background:
    Clusterin functions as extracellular chaperone that?prevents aggregation?of?nonnative?proteins.?It?also?functions?as
    extracellular chaperone that?prevents aggregation of?nonnative?proteins.?It’s?intracellular form?suppresses stress-induced?apoptosis?by stabilizing?mitochondrial?membrane?integrity through?interaction with?HSPA5.
    Clusterin?is detected?in?blood?plasma, cerebrospinal fluid,?milk, seminal?plasma?and?colon?mucosa.??It’s?also?detected?in?brain,?testis, ovary,?liver and?pancreas, and at?lower?levels?in?kidney,?heart,?spleen?and?lung.
    Clusterin?has?been?shown?to?stain?95% of?systemic?ALCL,?including?100% of?ALK-1(+)?and?91% of?ALK-1(-)?ALCL. Studies?have shown that clusterin?may?be a?useful diagnostic?marker for ALCL,?especially?in?ALK-1(-)?cases.?Overexpression?of?clusterin
    appears to?be a?useful?prognostic factor for?patients with ovarian?carcinomas.
    Subcellular?location:
    Secreted
    Recommended?Method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Recombinant?protein fragment of Clusterin was?used?as an?immunogen. This?information?is?proprietary to??Biolynx.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage Conditions:
    -25°C?to?-18°C
    Shipment?Instructions:
    Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
    Recommended?Dilution:
    IHC-P:?????1:100-1:200
    Background?References:
    1. ?PMID:11123922
    2. ?PMID:17322305
    Immunohistochemistry?(Formalin/PFA-fixed?paraffin-embedded????sections)?analysis?of??human?ALCL?labelling?Clusterin?with?BP6268.

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