• L1CAM兔單克隆抗體

    L1CAM兔單克隆抗體

    • 價(jià)格￥2200
    • 規格100ul
    • 貨號HKZ150403
    • 單位支
    • 品牌HaoKebio

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    HaoKebioHKZ150403L1CAM兔單克隆抗體100ul支2200
    L1CAM
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50280?Clone# ?BP6257
    Predicted?Molecular Wt:
    140kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID: ??P32004
    Background:
    L1CAM,a?neural cell adhesion?molecule which?is?involved?in the dynamics?of?cell?adhesion?and?in the?generation?of
    transmembrane signals at tyrosine?kinase?receptors.?During?brain development,?L1CAM?is critical?in?multiple?processes,
    including?neuronal?migration, axonal growth and fasciculation, and?synaptogenesis.?In?the?mature?brain,?L1CAM?plays?a?role?in the dynamics of?neuronal structure and?function,?including?synaptic?plasticity.
    L1CAM’s cytoplasmic expression?mainly?in?CNS,?PNS and distal?renal?tubules.
    L1CAM?has?become a?marker for evaluating the?malignancy and?prognosis?of?ovarian?cancer,?endometrial?cancer,?melanoma?and other?tumors.
    Subcellular?location:
    Cytoplasm
    Recommended?Method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Synthetic?peptide. This?information?is?proprietary to?Biolynx.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage Conditions:
    -25°C?to?-18°C
    Shipment?Instructions:
    Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
    Recommended?Dilution:
    IHC-P:?????1:100-1:200
    Background?References:
    Sch?fer,?M.?K.?E., et?al.?Neurobiology?of?Disease,?40(1),?222–237.
    Immunohistochemistry?(Formalin/PFA-fixed?paraffin-
    embedded?sections)?analysis of ?human?Kidney?labelling?L1CAM?with?BP6257.

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