• SF-1兔單克隆抗體

    SF-1兔單克隆抗體

    • 價(jià)格¥1000
    • 規格100ul
    • 貨號HKZ150382
    • 單位
    • 品牌HaoKebio

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    HaoKebioHKZ150382SF-1兔單克隆抗體100ul1000
    SF-1
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50259?Clone# ?BP6236
    Predicted?Molecular Wt:
    52kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID:??Q13285
    Background:
    SF-1?is a transcriptional activator that essential for?sexual?differentiation?and?formation?of the?primary?steroidogenic?tissues.?It?also activated?by the?phosphorylation of?NR5A1?by?HIPK3?leading to?increased steroidogenic?gene?expression?upon?cAMP
    signaling?pathway stimulation.
    SF-1?is?highly expressed?in the adrenal cortex,?ovary, testis,?spleen.
    SF-1?is generally?used for diagnosis of sex?cord-stromal tumors?and?differantial?diagnosis?of?adrenocortical?adenoma?and?pheochromocytoma.
    Subcellular?location:
    Nucleus
    Recommended?Method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
    Immunogen:
    Full?length?protein corresponding to?Human SF-1.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
    Storage Conditions:
    -25°C?to?-18°C
    Shipment?Instructions:
    Shipped?on?blue?ice.?Upon?delivery?store?at?-25°C?to?–?18°C. Avoid?freeze?/ thaw?cycles.
    Recommended?Dilution:
    IHC-P:?????1:100-1:200
    Background?References:
    1. ?Lan?H.-C.?Mol. Cell.?Biol.?27:2027-2036(2007)
    Immunohistochemistry?(Formalin/PFA-fixed?paraffin-
    embedded?sections)?analysis of adrenocortical adenoma?labelling?SF-1?with?BP6236.

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