• TROP-2兔單克隆抗體

    TROP-2兔單克隆抗體

    • 價(jià)格￥2200
    • 規格100ul
    • 貨號HKZ150354
    • 單位支
    • 品牌HaoKebio

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    HaoKebioHKZ150354TROP-2兔單克隆抗體100ul支2200
    TROP-2
    Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
    Catalog# ?BX50231?Clone# ?BP6208
    Predicted?Molecular Wt:
    36kDa
    Purity: ??ProA?affinity?purified?IgG
    Species Cross-reactivity:
    Human
    Form: ??Liquid
    Applications:
    IHC-P
    Swissprot?ID: ??P09758
    Background:
    TROP-2 or Tumor-associated calcium signal transducer?2,?also?known?as epithelial?glycoprotein-1?antigen?(EGP-1),?is?a?protein?that?in?humans?is encoded?by the TACSTD2 gene. This transmembrane glycoprotein functions?in?a variety?of?cell?signaling
    pathways and was first elucidated as?a transducer?of?an?intracellular?calcium?signal..
    TROP-2?is expressed?in a variety of epithelial?tissues?and?tumor?tissues?from?which?TROP2?originates,?such?as?tonsil,?esophagus,?pancreatic,?prostate and gastric cancers.
    TROP-2?has?become a?new target for?researchers to develop antibody-conjugated?drugs. TROP-2?is?highly?expressed?in?triple-??negative?breast cancer,?non-small cell?lung cancer,?uroepithelial carcinoma?and various?types?of?solid?tumors,?and?is?expected
    Subcellular?location:
    Membrane
    Recommended?method:
    Heat?induced epitope?retrieval with Tris-EDTA?buffer
    (pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)
    for?30?minutes.
    Immunogen:
    Synthetic?peptide. This?information?is?proprietary to?Biolynx.
    Storage?Buffer:
    PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA
    0.05%.
    Storage conditions:
    -25°C?to?-18°C
    Storage instructions:
    Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store
    at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
    Recommended?Dilutions:
    IHC-P:?????1:100-1:200
    Background?References:
    1. ?McDougall, A.R. et?al.?(2015)?Dev?Dyn?244,?99-109.
    2.?Shvartsur, A. and?Bonavida,?B.?(2015) Genes?Cancer?6,?84-105.
    Immunohistochemistry
    (Formalin/PFA-fixed?paraffin-
    embedded?sections)?analysis of
    human?esophageal?carcinoma
    tissue?labelling TROP-2 with
    BP6208.?Heat?mediated?antigen retrieval?was?performed?using????Tris/EDTA?buffer?pH?9.0

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