Von Willebrand Factor（VWF）兔單克隆抗體

價(jià)格￥600
規格100ul
貨號HKZ150202
單位支
品牌HaoKebio

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產(chǎn)品參數

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品牌	商品編碼	商品名稱(chēng)	規格	單位	單價(jià)
HaoKebio	HKZ150202	Von Willebrand Factor（VWF）兔單克隆抗體	100ul	支	600

Von?Willebrand?Factor?(VWF)
Recombinant?Rabbit?Monoclonal Antibody?Product?Datasheet
Catalog# ?BX50079?Clone# ?BP6084
Predicted?Molecular Wt:
309kDa
Purity: ??ProA?affinity?purified?IgG
Species Cross-reactivity:
Human
Form: ??Liquid
Applications:
IHC-P
Swissprot?ID: ??P04275
Background:
Human von Willebrand factor?(VWF,or factor VIII-related antigen)?is?a?309?kDa?multimeric?plasma?glycoprotein,?important?in????the?maintenance of?hemostasis,?it?promotes adhesion of?platelets to the sites?of?vascular?injury?by?forming?a?molecular?bridge?between sub-endothelial collagen?matrix and?platelet-surface?receptor complex?GPIb-IX-V. Von?Willebrand?factor?also?acts?as??a chaperone for coagulation factor VIII, delivering?it?to?the?site?of?injury,?stabilizing?itsheterodimeric?structure?and?protecting??it from?premature clearance from?plasma.
Von Willebrand factor?is synthesized?by endothelial cells?and?is?reported?to?be?expressed?in?a?number?of tumors?of vascular
origin.?IHC?resultsaid?in the classification of acute?myeloid?leukemia?FAB type?M7, angiosarcoma?and?epithelioid?hemangioendothelioma.
Subcellular?location:
Cytoplasm
Recommended?method:
Heat?induced epitope?retrieval with Tris-EDTA?buffer???(pH?9.0),?primary?antibody?incubate?at?RT?(18°C-25°C)?for?30?minutes.
Immunogen:
Synthetic?peptide corresponding to?residues within
aa1150-1250 of?von?Willebrand?factor?was?used?as?an immunogen.
Storage?Buffer:
PBS?59%, Sodium?azide?0.01%,?Glycerol?40%,?BSA 0.05%.
Storage conditions:
-25°C?to?-18°C
Storage instructions:
Shipped on?blue?ice.?Upon delivery,?aliquot,?and?store?at?-25°C?to?-18°C. Avoid?freeze?/?thaw?cycles.
Recommended?Dilutions:
IHC-P:?????1:100-1:200
Background?References:
1.?Weidner?N, Semple?JP, Welch?WR,?Folkman?J.?N?Engl?J Med?1991,324:1-8.
2.?ObermairA, Wanner C,?BilgiS,Speiser?P, et al.?Am J?Obstet?Gynecol?1998?Feb;178(2):314-319.
Immunohistochemistry
(Formalin/PFA-fixed
paraffin-embedded
sections)?analysis of
Cervix?labelling VWF with?BP6084.?Heat?mediated ???antigen?retrieval?was
performed?using
Tris/EDTA?buffer?pH?9.0

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