• 甲狀腺轉錄因子-1TTF-1）兔單克隆抗體

    甲狀腺轉錄因子-1TTF-1）兔單克隆抗體

    • 價(jià)格￥11550
    • 規格1ml
    • 貨號HKI0621B
    • 單位支
    • 品牌HaoKebio

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    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHKI0621B甲狀腺轉錄因子-1TTF-1）兔單克隆抗體1ml支11550

    Applications

    Tested Applications:
    IHC, WB,ELISA
    Cited Applications:
    WB

    ?

    Species Specificity:
    human, pig
    Cited Species:
    human
    Positive WB detected in:
    HepG2 cells
    Positive IHC detected in:

    human thyroid cancer tissue, human lung cancer tissue

    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Recommended dilution:
    WB : 1:1000-1:8000
    IHC : 1:50-1:500

    Product Information

    Source:
    Mouse
    Purification method:
    Protein A purification
    Isotype:
    IgG3
    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.

    Immunogen Information

    Immunogen:
    Peptide
    Full name:
    NK2 homeobox 1
    Calculated molecular weight:
    42 kDa
    Observed molecular weight:
    41 kDa
    ?
    ?
    Gene symbol
    NKX2-1
    Synonyms
    BHC, Homeobox protein Nkx 2.1, NK 2, NK2 homeobox 1, NKX2 1, NKX2.1, NKX2-1, NKX2A, TEBP, Thyroid nuclear factor 1, Thyroid transcription factor 1, TITF1, TTF 1, TTF1

    Background

    Homeobox protein Nkx-2.1 (NKX2-1), also named Thyroid nuclear factor 1,Thyroid transcription factor 1(TTF1). It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea (BHC), choreoathetosis, hypothyroidism, and neonatal respiratory distress (CHNRD).

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