• BCL2L1兔多克隆抗體

    BCL2L1兔多克隆抗體

    • 價(jià)格￥2800
    • 規格200ul
    • 貨號HK210039L
    • 單位支
    • 品牌HaoKebio

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    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHK210039LBCL2L1兔多克隆抗體200ul支2800


    Applications

    Tested Applications:
    FC, IF, IHC, IP, WB,ELISA
    Cited Applications:
    CoIP, IHC, WB

    Species Specificity:
    human, mouse

    Cited Species:
    human, mouse, rat

    Positive WB detected in:
    NIH/3T3 cells, RAW 264.7 cells

    Positive IP detected in:
    NIH/3T3 cells

    Positive IHC detected in:
    human testis tissue, human lung cancer tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Positive IF detected in:
    HepG2 cells

    Positive FC detected in:
    Jurkat cells

    Recommended dilution:
    WB : 1:500-1:2000
    IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
    IHC : 1:50-1:500
    IF : 1:50-1:500
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information

    Full name:
    BCL2-like 1

    Calculated molecular weight:
    26 kDa

    Observed molecular weight:
    30 kDa



    Gene symbol
    BCL2L1

    Synonyms
    Apoptosis regulator Bcl X, BCL2L1, Bcl-xL
    Background
    BCL2L1 is a member of the BCL-2 protein family. BCL2L1 is expressed as three isoforms, Bcl-X(L),Bcl-X(s) and Bcl-X(beta), and is located at the outer mitochondrial membrane. The Bcl-XL isoform is a 233 amino acid protein, acting as an apoptotic inhibitor. Bcl-XL can forms heterodimers with BAX, BAK or BCL2, and the heterodimerization with BAX does not seem to be required for anti-apoptotic activity. The Bcl-XS isoform is a shorter variant that is 178 amino acids in length and lacks a 63 amino acid region (amino acids 126-188), acting as an apoptotic activator. This antibody can recognize Bcl-XL, Bcl-XS and Bcl-X(Beta).

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