• IL18兔多克隆抗體

    IL18兔多克隆抗體

    • 價(jià)格￥1200/￥2800
    • 規格50ul/200ul
    • 貨號HK210191S/HK210191L
    • 單位支
    • 品牌HaoKebio

    產(chǎn)品介紹
    產(chǎn)品參數
    資料下載
    品牌商品編碼商品名稱(chēng)規格單位單價(jià)
    HaoKebioHK210191SIL18兔多克隆抗體50ul支1200
    HaoKebioHK210191LIL18兔多克隆抗體200ul支2800

    Applications
    Tested Applications:
    IF, IHC, IP, WB, ELISA

    Cited Applications:
    IF, IHC, WB
    Species Specificity:
    human

    Cited Species:
    human, rat

    Positive WB detected in:
    HeLa cells, A431 cells, HaCaT cells, DU 145 cells

    Positive IP detected in:
    HeLa cells

    Positive IHC detected in:
    human tonsillitis tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Positive IF detected in:
    HeLa cells

    Recommended dilution:
    WB : 1:1000-1:4000
    IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
    IHC : 1:50-1:500
    IF : 1:10-1:100
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information

    Full name:
    IL-18

    Calculated molecular weight:
    193 aa, 22 kDa

    Observed molecular weight:
    22 kDa


    Gene symbol
    IL18

    Synonyms
    Iboctadekin, IFN gamma inducing factor, IGIF, IL 1 gamma, IL 18, IL 1g, IL18, IL-18, IL1F4, Interleukin 1 gamma, Interleukin 18, Mature IL18, pre IL18, Pre-IL18
    Background
    IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release IFN gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 22 kDa precursor and then cleaved into a biologically activate 18 kDa form. This antibody 10663-1-AP is raised against the full length IL18 precursor, and it recognizes both the pre-IL18 and mature IL18 theoretically.sue, human hepatocirrhosis tissue
    Note: suggested antigen retrieval with?TE buffer pH 9.0;?(*) Alternatively, antigen retrieval may be performed with?citrate buffer pH 6.0

    Recommended dilution:
    WB : 1:500-1:2000
    IHC : 1:50-1:500
    Product Information

    Source:
    Rabbit

    Purification method:
    Antigen affinity purification

    Isotype:
    IgG

    Storage:
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
    Store at -20°C. Stable for one year after shipment.?Aliquoting is unnecessary for -20oC storage.
    Immunogen Information

    Full name:
    interleukin 6 (interferon, beta 2)

    Calculated molecular weight:
    212 aa, 24 kDa

    Observed molecular weight:
    20 kDa

    Gene symbol
    IL6

    Synonyms
    B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HSF, Hybridoma growth factor, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6
    Background
    Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.

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